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Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and

Jennica L. Zaro,Wei-Chiang Shen

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 4,   Pages 407-427 doi: 10.1007/s11705-015-1538-y

Abstract: Over the past few decades, cell penetrating peptides (CPPs) have become an important class of drug carriers

Keywords： cell penetrating peptides     amphipathic peptides     drug delivery    

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Significance and strategies in developing delivery systems for bio-macromolecular drugs

Huining HE, Qiuling LIANG, Meong Cheol SHIN, Kyuri LEE, Junbo GONG, Junxiao YE, Quan LIU, Jingkang WANG, Victor YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 496-507 doi: 10.1007/s11705-013-1362-1

Abstract: the drug on tumor cells as opposed to normal tissues, and (2) the lack of ability to cross the tumor cell

Keywords： delivery systems     bio-macromolecular drugs     cell penetrating peptides    

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Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 9-19 doi: 10.1007/s11705-013-1306-9

Abstract: research, an innovative silica-based, mucoadhesive oral insulin formulation with encapsulated-insulin/cellpenetrating peptide (CPP) to overcome both enzyme and mucosal barriers is discussed, and the preliminaryIt was also confirmed that low molecular weight protamine (LMWP) behaves like a CPP peptide, with a cell

Keywords： insulin     cell penetrating peptide     mucoadhesive composites     oral delivery    

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Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Strategic Study of CAE 2003, Volume 5, Issue 11,   Pages 25-33

Abstract:

The history and the actualities of developing earth-penetrating weapon are described.The technical difficulties for developing low-yield earth-penetrating nuclear weapons have not been primaryThe experimental results indicate that there is a favorable analogical relation among earth-penetratingA method for calculating profiles on acceleration, velocity and displacement of penetrating projectileupon penetrating depth data is introduced.

Keywords： test of weapon     earth penetrating     gas gun     impact     experimental technique    

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Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 5,   Pages 889-901 doi: 10.1007/s11705-020-1919-8

Abstract: Owing to ECs-targeting ability, cell-penetrating ability and nuclear targeting capacity of REDV-G-TAT-G-NLS

Keywords： gene carriers     multitargeting function     ECs     transfection efficiency    

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Enzyme-instructed self-assembly of peptides containing phosphoserine to form supramolecular hydrogels

Jie Zhou, Xuewen Du, Jiaqing Wang, Natsuko Yamagata, Bing Xu

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 509-515 doi: 10.1007/s11705-017-1613-7

Abstract: phosphatase, but the study of the substrates of phosphatases mainly focuses on the phosphotyrosine containing peptidesIn this work, we examine the EISA of phosphoserine containing small peptides for the first time by designingprovides insights on how the specific molecular structures influence self-assembling behaviors of small peptidesMoreover, the utilization of D-amino acids largely enhances the biostability of the peptides, thus providing

Keywords： enzyme-instructed self-assembly     phosphoserine     phosphatase     supramolecular hydrogel    

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The damage effect of earth penetrating weapons and key scientific problems of deep buried protective

Fan Pengxian,Qian Qihu,Wang Mingyang

Strategic Study of CAE 2013, Volume 15, Issue 5,   Pages 47-58

Abstract: The earth penetrating weapons (nuclear and non-nuclear) developing by countries with military power haveOn the summary of the developing earth penetrating weapons, the damage effects of earth penetrating weaponsare reviewed, with emphasis on penetrating effect, crater effect and explosion ground shock effect.

Keywords： earth penetrating weapons     damage effect     deep buried     protective engineering    

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to: Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 1,   Pages 220-220 doi: 10.1007/s11705-020-1995-9

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Reverse-Time Migration from Rugged Topography to Image Ground-Penetrating Radar Data in Complex Environments Article

John H. Bradford,Janna Privette,David Wilkins,Richard Ford

Engineering 2018, Volume 4, Issue 5,   Pages 661-666 doi: 10.1016/j.eng.2018.09.004

Abstract: text-align:justify">In ground-penetrating

Keywords： Ground-penetrating radar     Reverse-time migration     Sand dune     Amplitude analysis    

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Experimental investigation of lavge-loading projectile penetrating

Zhao Shengwei,Gu Renhong,Chu Zhe,Li Ming

Strategic Study of CAE 2009, Volume 11, Issue 8,   Pages 44-47

Abstract: Axial acceleration was evaluated by SAPLL. penetration process of projectile on penetrating concretePenetration depth and structure intensity of projectile were examined by a series of experiments on penetratingA conclusion is obtained, projectile isn't destroyed during penetrating concrete target,and reinforced

Keywords： thin-walls projectile     concrete     penetration depth    

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Microfluidics for cell-cell interactions: A review

Rui Li,Xuefei Lv,Xingjian Zhang,Omer Saeed,Yulin Deng

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1,   Pages 90-98 doi: 10.1007/s11705-015-1550-2

Abstract: The well-designed microscale intermediary is also ideal for the study of cell biology.Particularly, microfluidic chip is helpful for better understanding cell-cell interactions.

Keywords： microfluidic chip     co-culture     cell-cell interactions     review    

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Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: 645 cardiac cells were generated from embryonic day 17.5 and postnatal days 2 and 8 mice by single-cellMNDCMs having interactions with macrophages and non-proliferative MNDCMs (non-pMNDCMs) with minimal cell–cellThese MNDCMs were mapped to the heart by integrating the spatial and single-cell transcriptomic data.In conclusion, a novel non-pMNDCM subpopulation with minimal cell–cell communications was unveiled, highlighting

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing    

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Deubiquitinases as pivotal regulators of T cell functions

Xiao-Dong Yang, Shao-Cong Sun

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 451-462 doi: 10.1007/s11684-018-0651-y

Abstract: Defect in T cell activation is associated with severe immune deficiencies, whereas aberrant T cell activationAn emerging mechanism that regulates T cell activation and tolerance is ubiquitination, a reversibleIt is now well recognized that DUBs are crucial regulators of T cell responses and serve as potential

Keywords： deubiquitinase     ubiquitination     T cell activation     T cell differentiation     T cell tolerance    

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Cell surface protein engineering for high-performance whole-cell catalysts

Hajime Nakatani,Katsutoshi Hori

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 46-57 doi: 10.1007/s11705-017-1609-3

Abstract: Cell surface protein engineering facilitated by accumulation of information on genome and protein structureinvolves heterologous production and modification of cell surface proteins using genetic engineering, and is important for the development of high-performance whole-cell catalysts.In this field, cell surface display is a major technology by exposing target proteins, such as enzymes, on the cell surface using a carrier protein.

Keywords： cell surface engineering     surface display     whole-cell catalysts     bioprocess    

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Stem cell niches and endogenous electric fields in tissue repair

Li LI, Jianxin JIANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 40-44 doi: 10.1007/s11684-011-0108-z

Abstract: Endogenous adult stem cells reside in certain regions of organs, known as the stem cell niche, whichMany regulatory factors are involved in the stem cell-based repair process, including stem cell nichesHere we briefly review the role of stem cell niches and endogenous electric fields in tissue repair,and hypothesize that endogenous electric fields become part of stem cell niche in the wound site.

Keywords： stem cell     stem cell niche     electric field     tissue repair    

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Title Author Date Type Operation

Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and

Jennica L. Zaro,Wei-Chiang Shen

Journal Article

Significance and strategies in developing delivery systems for bio-macromolecular drugs

Huining HE, Qiuling LIANG, Meong Cheol SHIN, Kyuri LEE, Junbo GONG, Junxiao YE, Quan LIU, Jingkang WANG, Victor YANG

Journal Article

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Journal Article

Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Journal Article

Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Journal Article

Enzyme-instructed self-assembly of peptides containing phosphoserine to form supramolecular hydrogels

Jie Zhou, Xuewen Du, Jiaqing Wang, Natsuko Yamagata, Bing Xu

Journal Article

The damage effect of earth penetrating weapons and key scientific problems of deep buried protective

Fan Pengxian,Qian Qihu,Wang Mingyang

Journal Article

to: Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Journal Article

Reverse-Time Migration from Rugged Topography to Image Ground-Penetrating Radar Data in Complex Environments

John H. Bradford,Janna Privette,David Wilkins,Richard Ford

Journal Article

Experimental investigation of lavge-loading projectile penetrating

Zhao Shengwei,Gu Renhong,Chu Zhe,Li Ming

Journal Article

Microfluidics for cell-cell interactions: A review

Rui Li,Xuefei Lv,Xingjian Zhang,Omer Saeed,Yulin Deng

Journal Article

Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Journal Article

Deubiquitinases as pivotal regulators of T cell functions

Xiao-Dong Yang, Shao-Cong Sun

Journal Article

Cell surface protein engineering for high-performance whole-cell catalysts

Hajime Nakatani,Katsutoshi Hori

Journal Article

Stem cell niches and endogenous electric fields in tissue repair

Li LI, Jianxin JIANG

Journal Article